Squamous cell carcinoma (SCC) is a skin cancer that arises from squamous cells in the outer layers of the skin. On the trunk and limbs it is most common on the forearms, backs of the hands, lower legs, shoulders and upper back, and it is usually the result of accumulated ultraviolet exposure. SCC is the second most common skin cancer in Australia after BCC.
An SCC on the body typically appears as a firm, raised, tender lump, or as a thickened scaly patch that crusts, bleeds and does not settle. On the lower leg it can look like a small ulcer or a wound that will not heal. Many arise in skin that already shows sun damage, and some develop from a solar keratosis over weeks to months.
SCC can grow faster than BCC and has some capacity to spread to lymph nodes, particularly when a lesion is large, thick, recurrent, or arising in a scar or a long standing wound. For that reason an SCC is generally removed promptly. If you have a lump or sore on your arm, leg, chest or back that has not healed within a few weeks, see your GP or dermatologist, and do not delay if it is changing quickly.
Assessment includes examining the lesion with dermoscopy, checking the rest of your skin for other sun damage, and feeling the draining lymph nodes in the armpit, groin or neck depending on where the lesion sits.
Diagnosis is confirmed by biopsy and histopathology. The report gives the thickness, the degree of differentiation, the depth of invasion and whether tumour is tracking along nerves. These features determine the margin taken at surgery and whether imaging, lymph node assessment or multidisciplinary discussion is recommended.
Surgical excision with a margin is the standard treatment for SCC on the trunk and limbs. Radiotherapy is an alternative in selected cases and is directed by a radiation oncologist. Larger lesions on the limbs often need reconstruction rather than direct closure.
Timeframes vary with the size of the excision, the method of closure and the site. Lower limb wounds and skin grafts generally take longer than wounds on the trunk.
Dr Maryam Seyedabadi, Specialist Plastic Surgeon, MBBS FRACS, AHPRA MED0001341746, consults at 2c Heeley Street, Paddington and operates at St Luke’s Hospital in Potts Point, East Sydney Private Hospital, Sydney Day Hospital, Double Bay Day Hospital and The Skin Hospital in Darlinghurst. With a referral from your GP or dermatologist, a Medicare rebate can be claimed for these procedures.
Because outcomes depend on the type, size, site and stage of the lesion, your plan is confirmed once your examination and pathology have been reviewed, and it may change if the report indicates that more tissue needs to be removed. To arrange a consultation in Sydney, call 1300 067 668.
Squamous cell carcinoma, or SCC, is a skin cancer that arises from cells in the outer layer of the skin. On the arms, hands, legs, back and chest it often appears as a firm scaly lump, a thickened crusted patch, or a tender sore that bleeds and does not heal over several weeks. It can grow over weeks to months, faster than a basal cell carcinoma.
Your GP or dermatologist will examine the lesion and take a biopsy, and diagnosis is confirmed by histopathology. The report describes depth, differentiation and any nerve involvement, which indicates whether the lesion is higher risk. Examination of nearby lymph nodes, and sometimes imaging such as ultrasound, may be arranged. A referral allows a Medicare rebate to be claimed for these procedures.
The margin taken depends on the size, depth and features reported on your biopsy, so it varies between lesions. Wider excisions on the shin, forearm, shoulder or back may not close directly and can need a local flap or a skin graft. The specimen is sent to pathology so the margins can be assessed, and further surgery is sometimes needed if they are not clear.
Risk varies with the type, size, site and stage of the lesion and with your general health, and it is higher for thicker or poorly differentiated lesions. Because local recurrence and spread to lymph nodes are possible, planned reviews of the scar and surrounding area matter, along with regular skin checks. Report any new lump, thickening or non-healing sore to your GP or dermatologist.